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Grape Seed Extract Vs Quercetin 

Grape Seed Extract Vs Quercetin


Disclaimer: This content has been produced purely for informational and educational purposes only and is never intended to be used as a substitute for professional medical guidelines including diagnosis, advice, and treatment.  


The grape seed extract is densely packed with plant nutrients, especially polyphenol-rich compounds such as flavonoids, proanthocyanidins, and anthocyanins. One of the primary flavonoids naturally found in grape seed extract is quercetin. Quercetin can also be found in many other sources as well. Grape seed extract and quercetin have myriad potential benefits. Quercetin is used alone or in combination with grape seed extract. But - grape seed extract vs quercetin - which one is more efficient? Let’s try to find it out together. 

In this article, we’ll place grape seed extract vs quercetin against each other on the basis of their medicinal values and potential benefits. But before we get into the difference between grape seed extract and quercetin, we'll need to learn the basics of these ingredients a little bit more. So, let’s get started. 

Table of contents 

  • What is grape seed extract? 
  • What is quercetin? 
  • Grape seed extract vs quercetin: medicinal values 
  • Grape seed extract vs quercetin: potential benefits  
  • Final words 

What is grape seed extract? 

Grape seed extract, also known as GSE, is a dietary supplement that is prepared from crushed grape seeds. The plant species of grape is botanically known as Vitis vinifera which is endemic to the Mediterranean, Europe, and some Asian regions of surround the Caspian Sea. The juicy fruits are widely used in winemaking, which is why they are also called wine grapes as well. 

The seeds of grapes are isolated, dried, and pulverized to turn into a concentrated extract that is densely packed with a range of plant nutrients and comes in various supplementary forms such as capsules, tablets, and liquid extracts. The nutritional compounds found in grape seed extract have been found to have diverse potential benefits ranging from protecting the heart to repairing damaged tissues to preventing the growth of cancer cells.   

What is quercetin? 

Quercetin is a plant chemical (phytochemical) that belongs to a large class of bioflavonoids responsible for the varying natural colors of many fruits, flowers, and vegetables. It’s found in a range of foods and plants including berries, apples, green teas, nuts, cherries, olive oils, and various colorful vegetables such as raw red onions, kale, broccoli, capers, and tomatoes. It’s also found in wine grapes, which is why grape seed extract contains significant quantities of quercetin as well.  

Grape seed extract vs quercetin: medicinal values 

Grape seed extract contains a large number of varying plant nutrients, especially polyphenol-rich plant chemicals such as flavonoids, anthocyanins, and proanthocyanidins. The most prevalent flavonoids present in grape seed extract are catechin, epicatechin, and of course, quercetin. 

Though the health potentials of grapes have been known to humans historically for thousands of years, the use of grape seed extract in medicine is relatively new, particularly in modern medicine. Active compounds present in grape seed extract have been believed to have many different medicinal properties.  

The most noticeable medicinal properties of grape seed extract include anti-inflammatory and antioxidant effects that are highly helpful in protecting the cardiovascular system including blood vessels. This lowers the risk of stroke and heart attack.  

On the other hand, quercetin has long been identified as an exceptional flavonoid mainly in terms of its tremendous antioxidant actions. It also has noticeable anti-inflammatory, anti-carcinogenic, and antiviral properties that can hugely help prevent the development of chronic inflammatory diseases and even reduce cancer risk.  

Grape seed extract vs quercetin: potential benefits 

Potential benefits of grape seed extract 

  • Increases blood flow 
  • Helps treat conditions related to blood vessels such as chronic venous insufficiency and atherosclerosis, a condition where plaques build up in or around the walls of the blood vessels 
  • Reduces blood pressure 
  • Lowers the risk of blood clot formation through blood thinning effects 
  • Supports brain function 
  • Prevents age-related oxidative damage of brain and nerve cells
  • Strengthens bones 
  • Protects the skin from sun damage
  • Improves skin appearance by reducing wrinkles and fine lines through anti-aging effects 
  • Helps heal wounds faster 
  • Protects and supports kidney functions 
  • Assists the liver to detox itself and the body
  • Reduces oxidative stress throughout body cells
  • Reduces cancer risks   

Potential benefits of quercetin 

  • Helps lower inflammation 
  • Strengthens cardiovascular health 
  • Helps improve immune response and keep it in a balanced state 
  • Helps combat allergies 
  • Helps alleviate pain associated with various conditions such as arthritis and bladder infections
  • May help improve skin health
  • Helps protect liver health 
  • May help enhance energy and endurance 
  • Helps fight against cancer 

Final words 

When we compare grape seed extract vs quercetin, we find they both have exceptional antioxidant properties along with many other health potentials. Their effects are pretty similar. So which one is better? It all depends on how a person’s body responds to them according to personal health status. 

You may like grape seed extract if you want to:

  • Combat chronic venous insufficiency 
  • Improve blood flow 
  • Balance cholesterol levels 
  • Reduce blood pressure 

And, you might like quercetin if you want to: 

  • Lower inflammation (both chronic and acute)
  • Balance immune response 
  • Improve allergic symptoms 
  • Reduce the risk of cardiovascular ailments 

But these are only a few potential benefits and there are many more. Besides, dietary supplements may interact with other herbs and medicines and also can cause side effects. Therefore, it’s highly recommended to consult with a naturopathic doctor or dietician prior to using any supplements for any reason.

Here you can see Vorst’s Premium Grape Seed Extract Capsules 

Here you can see Vorst’s high-quality Quercetin 500 Mg Vegan Capsules

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