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Gamma-Aminobutyric acid (GABA) for ADHD




Disclaimer: This content has been produced purely for informational and educational purposes only and is never intended to be used as a substitute for professional medical guidelines including diagnosis, advice, and treatment. 

Some people believe that some groups may have a GABA shortage, however, this is just a theory at this point. This group includes those who exhibit signs of Attention Deficit Hyperactivity Disorder (ADHD), autism, anxiety, and depression. Some people report experiencing symptoms such as brain fog, mood swings, increased stress, anxiety, sadness, sleeplessness, irritability, and aggressiveness when they do not have enough of this neurotransmitter in their brains.


Table of Contents

  • Gamma-Aminobutyric acid for ADHD
  • What is gamma-aminobutyric acid (GABA)?
  • How does gamma-aminobutyric acid (GABA) work?
  • What Is ADHD?
  • Symptoms and Diagnosis
  • The Causes of ADHD
  • Gamma-Aminobutyric acid for ADHD
  • Precautions of Taking GABA
  • Final Words
  • Sources

What is gamma-aminobutyric acid (GABA)?

Gamma-aminobutyric acid, often known as GABA, is a neurotransmitter, which means that it is a chemical messenger in the brain. It does this by inhibiting certain impulses in the central nervous system, which causes your brain to function more slowly (your brain and spinal cord).

The neurotransmitter GABA is famous for its ability to induce feelings of calm. It is believed to play a significant part in regulating the hyperactivity of nerve cells, which is linked to feelings of anxiety, stress, and terror. Scientists also term GABA a non-protein amino acid neurotransmitter.

How does gamma-aminobutyric acid (GABA) work?

If you look at the inhibitory neurotransmitters in your brain, GABA is by far the most prevalent. Inhibitory neurotransmitters serve to dampen the activity of brain cells by preventing or blocking chemical communication. The actions of several neurotransmitters are quite similar. These chemicals relay information from one brain cell to another. A synapse is the small, fluid-filled gap that separates each nerve cell in the body. Across this synapse, neurotransmitters travel in search of particular receptors on the receiving nerve cell.

When it comes to GABA receptors, nerve cells have two options: GABA-A and GABA-B. GABA has a variety of receptors that all serve the same purpose by reducing a nerve cell's reactivity when bound by GABA. Because of its role as an inhibitory neurotransmitter, GABA reduces a nerve cell's capacity to receive, produce, or transfer chemical information to other nerve cells.

What Is ADHD?

Attention deficit hyperactivity disorder, sometimes known simply as ADHD, is a complicated brain illness that affects around 11% of children and nearly 5% of adults. Hyperactivity-Hyperactivity Disorder (ADHD) is a developmental disorder of the executive processes of the brain. People who suffer from ADHD struggle to control their impulses remain focused and stay organized.

The condition known as ADHD is not a behavior problem. The condition known as ADHD is not a mental disorder. The condition known as ADHD is not a distinct kind of learning impairment. Instead, attention deficit hyperactivity disorder (ADHD) is a developmental defect of the self-management system in the brain. ADHD is a condition that may be diagnosed in both adults and children.

Symptoms and Diagnosis

There is a good chance that many youngsters have trouble being still, waiting their turn, paying attention, avoiding fidgeting, and controlling their impulses. On the other hand, children who satisfy the diagnostic criteria for ADHD are distinguished by the fact that their symptoms of hyperactivity, impulsivity, organization, and/or inattention are considerably more severe than what would be anticipated for their age or level of development. These symptoms lead to substantial discomfort and may create issues at home, school, or work, as well as in relationships with other people. The observed symptoms are not due to the person being disobedient or being unable to grasp the duties or directions being given.

There are three main types of ADHD:

  • Predominantly inattentive presentation.
  • Predominantly hyperactive/impulsive presentation.
  • Combined presentation.

The existence of symptoms that have persisted over a length of time and have been evident throughout the course of the most recent six months is required in order to arrive at a diagnosis. Despite the fact that a diagnosis of ADHD may be made at any age, the onset of this condition occurs in childhood. When making a diagnosis, the symptoms must have been present before the person reaches the age of 12 and must have caused problems in more than one environment. For instance, the symptoms could manifest themselves in other places outside the house.

The Causes of ADHD

The root reasons for ADHD remain unknown to researchers. Several genes have been linked to ADHD, and although this is a strong indicator that genetics play a role, the exact gene or set of genes responsible for ADHD has yet to be determined. It's worth noting, too, that ADHD doesn't only affect the person who has it. Youngsters with attention deficit hyperactivity disorder (ADHD) have brains that vary from those of typically developing children. The amount of both grey and white matter in the brain is lower in children with ADHD, and they also show activation differences across brain regions while doing certain activities. More research has shown that people with ADHD have abnormalities in the brain's vermis, frontal lobes, and caudate nucleus. Low birth weight, early birth, exposure to chemicals (alcohol, smoking, lead, etc.) during pregnancy, and high stress during pregnancy are all outside of the realm of possibility when it comes to causing this illness.

Gamma-Aminobutyric acid for ADHD

There is just one research paper that can be considered credible on the topic of an imbalance of neurotransmitters in children who have ADHD. Children who were diagnosed with ADHD showed greater levels of the excitatory neurotransmitter glutamate than children who were not diagnosed with ADHD. In addition, they discovered that the ADHD group had lower levels of GABA than the control group. It is possible that an imbalance in the quantities of these brain chemicals is what causes the symptoms of ADHD, such as poor impulse control and hyperactivity. Even though the research was somewhat small, it still has some bearing on how we understand ADHD.

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Precautions of Taking GABA

There is an interaction between gamma-aminobutyric acid and hypertension drugs (GABA) GABA may have a hypotensive effect on blood pressure. Combining GABA with other medications that decrease blood pressure can cause dangerously low readings. Be sure to monitor your blood pressure regularly.

Final Words

As a comprehensive component in the treatment of ADHD, using GABA supplements has garnered quite the reputation in recent years. The recommended daily dose ranges from 100 to 200 milligrams, and can be taken up to three times.