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D3 and K2 for Optimal Absorption

 D3 and K2 for Optimal Absorption


Disclaimer: This content has been produced purely for informational and educational purposes only and is never intended to be used as a substitute for professional medical guidelines including diagnosis, advice, and treatment.


Table of Contents

  • Introduction
  • The Science behind Vitamin D3 and K2 Absorption
  • Benefits of Vitamin D3 and K2 Supplementation
  • Food Sources of Vitamin D3 and K2
  • Supplementation of Vitamin D3 and K2
  • Conclusion


Vitamins D3 and K2 are of utmost importance in the maintenance of optimal bone and overall health. Vitamin D3 is vital in the facilitation of the absorption of calcium and phosphorus from consumed food, both of which play a critical role in ensuring the durability of one's bones. Conversely, vitamin K2 assumes a pivotal function in the navigation of calcium towards the bones and its retraction from soft tissues like blood vessels and organs, thereby preventing calcification in these tissues.


The Science behind Vitamin D3 and K2 Absorption

Vitamin D3 is generated in the skin through exposure to sunlight or via ingestion from dietary sources. This vitamin is then converted into its active form, calcitriol, in the liver and kidneys. Calcitriol is responsible for the assimilation of calcium and phosphorus from the intestines, as well as regulating calcium levels in the bloodstream.

Vitamin K2 is present in fermented foods like cheese and natto. Upon absorption in the small intestine, it is transported to various tissues throughout the body, including both the bones and soft tissues. Once inside the cells, vitamin K2 activates proteins that serve to bind calcium and direct it towards the bones, while concurrently inhibiting its buildup in soft tissues.

The synergy between vitamins D3 and K2 is critical for optimal absorption and utilization. Vitamin D3 facilitates the production of proteins that depend on vitamin K2 for activation, such as osteocalcin. Osteocalcin is a protein that binds calcium to the bone matrix, thereby increasing bone strength. Vitamin K2 aids in the activation of another protein called matrix Gla protein, which helps to prevent the accumulation of calcium in soft tissues.


Benefits of Vitamin D3 and K2 Supplementation

Supplementation of one's dietary intake with vitamins D3 and K2 has been shown to confer numerous health benefits. One of the most remarkable advantages is the facilitation of better bone health and reduced susceptibility to fractures, particularly among elderly individuals. This is due to the fact that vitamin D3 assists the body in the absorption of calcium, while vitamin K2 ensures that the calcium is channeled to the bones where it is necessitated.

Another noteworthy health benefit of consuming vitamins D3 and K2 is the lower probability of developing cardiovascular disease. Various studies have demonstrated that these vitamins may help prevent the accumulation of calcium in the arteries, which is a primary cause of heart disease.

Moreover, the inclusion of vitamins D3 and K2 in one's diet may potentially improve dental health and decrease the risk of cavities. They have also been associated with potential health benefits for the immune system and brain.


Food Sources of Vitamin D3 and K2

Vitamin D3 can be found naturally in foods such as fatty fish including salmon, tuna, and mackerel, as well as fortified foods like milk, orange juice, and cereals. Vitamin K2, on the other hand, is present in fermented foods such as natto, sauerkraut, and kefir, as well as animal products including cheese, butter, and egg yolks.

For most adults, the suggested daily intake of vitamin D3 is between 600-800 IU, whereas the recommended daily intake of vitamin K2 is 90-120 micrograms. However, due to limited sun exposure or inadequate intake of natural food sources, many individuals may have a deficiency in these vitamins.

Supplementing with vitamins D3 and K2 can offer numerous health benefits, especially for bone and cardiovascular health. While natural food sources of these vitamins should be prioritized, supplementation may be necessary for those who have a deficiency or have limited access to these sources.


Supplementation of Vitamin D3 and K2

Vitamin D3 and K2 supplements are widely available in different dosages and forms, thus it is imperative to have a comprehensive understanding of these options prior to incorporating them into your dietary regimen. Generally, vitamin D3 supplements are marketed in dosages varying from 400 to 5000 IU, while vitamin K2 supplements are available in dosages ranging from 50 to 200 micrograms.

Distinct vitamin D3 supplement forms, such as tablets, capsules, and liquids, can be readily found in the market. Conversely, vitamin K2 supplements are commonly sold as either MK-4 or MK-7, with the latter being more bioavailable and having a prolonged retention period in the body.

It is critical to note that taking vitamin D3 and K2 supplements can potentially lead to side effects, including but not limited to vomiting, nausea, constipation, and an elevated risk of bleeding. Furthermore, these supplements may interact with certain medications, such as those intended for hypertension and blood thinning. As such, seeking guidance from a healthcare professional is necessary before embarking on a new supplement regimen.

It is highly recommended to select high-quality vitamin D3 or K2 supplements from reputable brands. Look for supplements that have undergone third-party testing to ensure both purity and potency. Consulting with a healthcare professional to determine the appropriate supplement type and dosage for your individual needs is also advised.


Vitamins D3 and K2 play crucial roles in maintaining overall health, particularly bone, and cardiovascular health. Supplementing with these vitamins can provide numerous benefits, including improved absorption and utilization of calcium, reduced risk of fractures and cardiovascular disease, and potential benefits for dental, brain, and immune system health.

It is important to choose high-quality supplements, consult with a healthcare provider, and be aware of potential side effects and interactions with other medications. By prioritizing these vitamins and ensuring adequate intake, individuals can support their overall health and well-being.


Check out Vorst’s supplements containing D3 and K2 below: 

Vitamin D3 1000 IU with Vitamin K2 Vegan Capsules

Vitamin D3 25 mcg (1000 IU) capsules

Vitamin D3 liquid 400 IU for Baby and Kid


References and Resources